Genomnia is a SME established in October 2008 with the aim of offering Next Generation Sequencing and Bioinformatic Analysis services. Recently we have progressed from the SOLID to the Ion Torrent technology, with which we are able to offer to Universities and Public or Private Research Centres in Italy and abroad a wide range of services, which include exome and genome analysis, personalized gene panels, transcriptome analysis, genome-wide epigenetic analyses (Chip-Seq and Methyl-Seq) and metagenomic analyses. In addition to the wide experience in molecular biology, the Company know-how extends to the sectors of bioinformatic analysis of massive sequencing data and high-throughput PCR applied to biomedical or to molecular genetics research projects.
Genomnia has adopted a new sequencing platform, Thermo Fisher/Life Technologies Ion Torrent, acquiring the Ion Personal Genome Machine® (PGM™) and the Ion S5. This platform of new technological conception is very flexible, with a production ranging from a minimum of 100 Meagbases to a maximum of 16 Gigabases of sequence for run. Its main application fields range from the study of mutations and gene alterations, with single-gene or disease-specific gene panels resequencing; to the human whole exome study; to the de novo sequencing or the resequencing of bacterial and viral genomes; to the study of transcriptome (RNA-seq, miRNA-seq, etc) and of epigenome (ChIP-seq, MBD-seq, Methyl-seq, etc.); till the study of the metagenomics of human microbiome and of other microbiomes using the 16S or whole-genome sequencing.
The laboratories are specifically organized according to the ThermoFisher/Life Technologies guidelines for a deep sequencing facility with the Ion Torrent platform, minimizing or zeroing the dangers of cross-contamination.
In this laboratory we perform the extraction, preparation and quality control of the samples delivered to Genomnia. In order to fulfill these activities the laboratory is fitted out with:
In this laboratory we prepare, through emulsion-PCR, the templated beads which will be loaded on the sequencing chips where the sequencing reaction will take place.
It is the laboratory where we perform the actual sequencing. It is fitted out with: