We have relevant experience in molecular biology and bioinformatic analysis of deep sequencing data applied to biomedical projects: transcriptome qualitative and quantitative analysis, miRNA identification and profiling, ncRNA identification and annotation, mutation detection, targeted genome resequencing and analysis.
Our experienced personnel takes care of the planning, optimization and analysis of your sequencing projects. We have upgraded our platform to the Applied Biosystems SOLID™ 5500XL-s with EZBead™ enrichment system, generating up to 180Gb per run . Fragment sequencing range from 25 up to 75bp, PE sequenging up to 75x35bp and mate paired sequencing up to 60x60bp.
Two base encoding system combined with the use of ECC (Exact Call Chemistry) Module allow a level of accuracy of 99.99% which makes it particularly suitable for genomic studies such as variation detection, especially for low frequency variants. The efficient barcoding system up to 96, permits safe and cost-effective multiplexing of large sample size projects. The wide dynamic range and sensitivity make it particularly suitable for measuring accurate fold changes at the low expression levels of RNA.